|
KMID : 0903520050480030280
|
|
Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2005 Volume.48 No. 3 p.280 ~ p.284
|
|
|
Antioxidant, Anticancer and Tyrosinase Inhibition Activities of Extracts from Rhododendron mucronulatum T.
|
|
An Bong-Jeun
Lee Chang-Eon
Son Jun-Ho
Lee Jin-Young
Choi Gui-Hyang
Park Tae-Soon
|
|
|
Abstract
|
|
|
|
Several biological activities of Rhododendron mucronulatum were investigated. The electron donating abilities of ethanol extracts of Rhododendron mucronulatum were more than 90% at 100 ppm, 500 ppm and 1,000 ppm. Xanthine oxidase was inhibition about 46% by the ethanol extracts of R. mucronulatum at 500 ppm 48% of tyrosinase activity relating to skin-whitening was shown at 1,000 ppm. Uniquely, the anti-microbial effects of water extract and ethanol extract were shown only on Staphylococcus aureus. The water extract 1 mg/disc showed the higher activity than ethanol extract. The growth inhibition effect of each sample on lung cancer (A549) and melanoma (B16F10) cell lines were over 70% at 1,000 ppm, while the effects on the melanoma (G361) and liver cancer (HepG2) were about 50% at the same concentration.
|
|
|
KEYWORD
|
|
|
Rhododendron mucronulatum, physiological activities, whitening
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|